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eosinophil cationic protein : ウィキペディア英語版
eosinophil cationic protein

Eosinophil Cationic Protein (ECP) also known as ribonuclease 3 is a basic protein located in the eosinophil primary matrix. In humans, the eosinophil cationic protein is encoded by the ''RNASE3'' gene.
ECP is released during degranulation of eosinophils. This protein is related to inflammation and asthma because in these cases, there are increased levels of ECP in the body.
There are three glycosolated forms of ECP and consequently ECP has a range of molecular weights from 18-22 kDa.〔Lee BioSolutions, Inc. http://www.leebio.com/eosinophil-cationic-protein-human-P359.html〕
== Function ==

Eosinophil cationic protein and the sequence related eosinophil-derived neurotoxin are both members of the ribonuclease a superfamily. Both proteins possess neurotoxic, helmintho-toxic, and ribonucleo-lytic activities. Eosinophil cationic protein is localized to the granule matrix of the eosinophil.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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